Immunosuppressive Components from an Ascomycete, Diplogelasinospora grovesii.

A Lectin from an Ascomycete Mushroom , Melastiza No

Using an aMnity adsorbent prepared from L-fucose and starch, a lectin was isolated from fruit bedies of an ascomycete mushroom, IVdlelastiza ch teri. The lectin was found to cross-react with antiserum against Aleuria aurantia lectin (AAL), that had been obtained £ rom another ascomycete mushroom. The N-termina] amino acid sequence was analyzed, and among 20 residues 12 were the same as AAL. The...

Crystal structure of an ascomycete fungal laccase from Thielavia arenaria

A New Marine Ascomycete from Australia

Most marine pyrenomycetes are lignicolous, but some are epiphytic on marine phanerogims and algae. Meyers (1957) listed 30 species of algae known to be attacked by these fungi. A number of reports dealing with marine ascomycetes on algal hosts appeared before 1900, the most noteworthy being those of Winter (1887), and Jones (1898). Cotton (1908) described a pyrenomycete on Ascophyllum nodosum (...

Polyketides from the ascomycete fungus Leptosphaeria sp.

The new polyketides leptosphaerins A-G (1-7) and the known compounds monodictysin B (8), 2-(2,6-dihydroxybenzoyl)-3-hydroxy-5-methylbenzoic acid (9), and 2-(2,6-dihydroxy-4-methylbenzoyl)-6-hydroxybenzoic acid (10) have been isolated from solid cultures of the ascomycete fungus Leptosphaeria sp. The absolute configurations of compounds 1, 2, and 6 were assigned using the modified Mosher method,...

Characterization of an Immunosuppressive Colon Cancer Cells' Factor Derived From

The colon cancer cell line, HT29, produces a soluble substance (HT29 factor) that blocks mitogeninduced T cell proliferation and the production of interleukin 2 (IL 2). Inhibition of T cell proliferation by the HT29 factor is reversible and is not due to a decline in cell viability or an alteration in the kinetics of T cell proliferation. I t occurs even when the HT29 factor is added only 24 hr...